Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job.

But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment.

We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Position: Senior Director/Director, Head of Cell Line Development, Global Upstream and Cell Line Development, Biologics DevelopmentLocation: NBRPosition SummaryThe Head of Cell Line Development NBR, Global Upstream and Cell Line Development (GUCLD) will be a member of the GUCLD Leadership Team and will lead a dedicated team in New Brunswick, NJ focusing on the development of mammalian cell lines in the production of monoclonal antibody and other types of recombinant proteins, including bi-specific antibody, fusion protein, and antibody drug conjugates, for clinical and commercial manufacturing. The incumbent will work closely with other functional groups within and outside of Biologics Development such as R&D, molecular biology, process development and process development analytics.

Key ResponsibilitiesThe Head of Cell Line Development NBR leads a high performing team through the following key responsibilities: Oversee cell line development key activities associated with production cell line development including transfection, selection, single cell cloning, high throughput screening, characterization of clonal cell lines using scale-down models, cell banking, and cell line stability studies.A key responsibility will be on providing guidance to the team on screening high producing clones for desired product quality and purity, and the identification of best manufacturable clonesEvaluate and introduce state of the art innovative technologies to improve cell line development process and therapeutic protein productionUnderstanding IP landscape of current and novel technologies in cell line development and developing a strategy to ensure freedom to operate.Managing cell line development projects with external partners and outsourcing activitiesManaging tech transfer activities to support cell banking, cell bank testing, and drug substance manufacturing Enable collaboration with functional teams in discovery, upstream and downstream process development, as well as analytical development teams to support drug substance development of BMS biologics pipelineServing as SME to represent cell line development in cross functional CMC teams as well as author/review regulatory filings for early and late-stage projectsWriting/reviewing technical reports and presenting data in internal meetingsSupervising direct reports and providing mentorship to a growing team.

Serve as Matrix team lead and member for cross functional business and administrative initiativesSupport budget - projections, actuals, monthly reporting, oversee capital asset management and laboratory operationsProvide leadership and management of staff including continued professional development for a team of 12-15 (direct, indirect, matrixed staff, contractors)Represent BMS in external conferences through oral presentationsQualifications & ExperiencePhD in Biological Sciences, Molecular Biology, Biochemical Engineering, or relevant discipline and minimum 8-10 years of relevant industrial experience, MS with over 12 years relevant experience.Extensive experience with cell line development for production of monoclonal antibody, fusion proteins, bi-specific antibody and other complex modalities of Biologics.Deep Molecular Biology understanding such as DNA cloning, vector construction and design, and genetic characterization of production cell banks is required.

Experience with high throughput screening and automation, immunological assays, and FACS requiredIn depth knowledge of antibody technology and protein expression as well as a good understanding of regulatory guidelines for human therapeutics.Proven record of publication in peer reviewed journals and presentations at conferences. Recognized as leader in the fieldStrong matrix leadership skills as well as direct people management experience with excellent track record of people talent development requiredDeep experience with biopharmaceutical development and managing a broad portfolio of projects of significant complexity and duration required.

This will require operational focus as well as ability to develop strategies and manage ambiguityExperience in Omics, synthetic biology, digital and data strategies is a plusExperience with AAV viral expression system development and production will be plusThe candidate must be well organized and have excellent oral and written communication skills.Demonstrated ability to think critically as well as possess excellent problem-solving skills.Distinction between Senior Director and Director will be based upon level of experienceIf you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway.

You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as Transforming patients' lives through science, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site ProtocolPhysical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer.

If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities.

As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations