Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job.

But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment.

We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.When you join BMS, you are joining a diverse, high-achieving team united by a common mission. BMS encompasses a broad range of disciplines to enable a robust pipeline of drug candidates aimed at serious diseases.

Chemistry is a core capability in Small Molecule & Drug Discovery with innovative scientists working in medicinal chemistry, radiochemistry, analytical chemistry, and large-scale synthesis. Within SMDD our Lead Discovery and Optimization (LDO) team is responsible for high throughput screening, compound storage and distribution, primary assays to support discovery programs, and compound profiling to explore drug liabilities in vitro. LDO scientists discover and adopt cutting edge assay technologies that utilize state-of-the-art automation to drive speed and efficiency.

Our Molecular Structure and Design team embraces novel approaches to computer-aided drug design, machine learning, and structural biology. The integration of these disciplines provides a seamless and highly interactive environment for discovery scientists to learn, develop, and innovate. Working in partnership with our disease area experts in the Thematic Research Centers provides an exciting pathway to discover and deliver medicines to patients in need.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.Principal Scientist, Leads Discovery and Optimization/Cellular Technologies GroupWe seek a highly motivated and innovative Principal Scientist to lead our Cellular Technologies Group which provides foundational cell biology to support Leads Discovery and Optimization's core mission to find and advance small molecule leads.

This prominent leadership position ensures the continuous supply of cultured and primary cells, organoids and induced pluripotent stem cells (iPSCs) to support high throughput screening activities as well as daily lead optimization assays. The candidate must possess extensive hands-on experience with mammalian cell culture, and will be expected to plan, execute and direct such work. The candidate must also have strong organizational skills to oversee a complex operation, managing a team of six scientists by assigning roles and responsibilities to ensure the delivery of cellular reagents required for efficient drug discovery operations.

In addition, the candidate must have extensive experience in development and application of iPSCs, organoids and other complex cellular models, and will be expected to scale these systems sufficiently to enable small molecule phenotypic screening campaigns. This leader will collaborate effectively across Bristol Myers Squibb's many research locations and work closely with our partner in India to produce a variety of cell-based reagents supporting experimental activities in the United States. This position is ideal for an individual who wants to be on the forefront of the drug discovery process to enrich the lives of patients.

The successful candidate will haveExtensive experience and command of the principals of mammalian cell culture and proven managerial success in enacting these principals in an industrial settingExperience with automated cell culturing systems such as the SelecT/CompacT would be considered a plusCommand of various primary cell isolation/differentiation and purification methodologiesSignificant experience in the maintenance, expansion, and differentiation of iPSCs to support genetic model development and phenotypic screensExtensive experience with the MaxCyte system to produce HTS quantities of transiently transfected cellsExperience with lentiviral transduction and production of engineered human T cellsPossess strong analytical and data analysis skillsAbility to manage projects across functional lines and geographic locationsStrong written & verbal communication skills for presenting data and ideas to multiple stakeholders across disciplinesWill have the ability to teaching and train new entry level scientistsAn intense desire to innovate, and apply new methods, technologies, and ideas to the field of drug discovery, and make a profound impact on the lives of patientsBasic Qualifications:Bachelor's Degree with 8+ years of academic or industry experienceOrMaster's Degree with 6+ years of academic or industry experienceOrPhD and 4+ years of academic or industry experiencePreferred Qualifications:PhD in Molecular/Cellular Biology, Biochemistry, Bioengineering or related field, with 4+ years' experience, and demonstrated expertise in the management of complex cell culture operationsExperience in supporting the development of complex biological disease-related cellular models by providing differentiated iPSCsExperience applying laboratory automation to mammalian cell cultureKnowledge of how CRISPR engineered cell lines are developedDemonstrated excellence in written and oral communicationStrong desire to succeed in cross-functional teams and collaborate in a highly matrixed environmentWorking knowledge of the overall drug discovery process would be considered a plusApplicants should be detail-oriented, highly organized, and able to multi-task with multiple projectsyou come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as Transforming patients' lives through science, every BMS employee plays an integral role in work that goes far beyond ordinary.

Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolPhysical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles.

Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations